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Colonic biopsies from these patients also show reduced GLP-1R expression, suggesting that decreased GLP-1 and GLP-1R expression may underlie the efficacy of ROSE-010 in alleviating IBS-C abdominal pain [61]

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In vitro functional assays, including luciferase and cAMP assays, were performed on cell lines expressing human and rat amylin and calcitonin receptors

Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes

Probiotics typically cause minor digestive adjustments